To access the Sequence settings in Salesforge you'd need to go to the dedicated tab in the Salesforge and click on the sequence name. Upon opening the sequence, you will be able to see in the upper-right part of the screen . Clicking on it will show the following:

Here we are in the Sequence builder, and we need to go for the 'Settings' where we will have the following settings with an explanation next to each one:

We do not recommend tracking open rates because it might impact the deliverability, furthermore, it shows to the recipient a warning message which can hurt the credibility of the e-mail.